The human skin loses approximately **1% of collagen per year** after the age of 20, a decline that accelerates visible aging signs like wrinkles and sagging. While traditional solutions like lasers or fillers focus on surface-level fixes, Rejuran collagen synthesis takes a regenerative approach by stimulating the body’s natural collagen production. Clinically proven to increase collagen density by **up to 30% within 12 weeks**, this treatment leverages polynucleotides (PN)—a core ingredient derived from salmon DNA—to repair damaged skin at the cellular level.
So, how does it work? Polynucleotides act as “messengers” that activate fibroblasts, the cells responsible for collagen synthesis. A 2022 study published in *Aesthetic Surgery Journal* revealed that patients receiving Rejuran treatments saw a **22% improvement in skin elasticity** compared to placebo groups. Unlike lasers, which often require **3–6 sessions** for visible results, Rejuran shows measurable changes after just **1–2 sessions**, with minimal downtime. Dermatologists like Dr. Emily Tan from Singapore’s Urban Clinic note, “It’s not just about smoothing wrinkles—it’s about rebuilding the skin’s foundation. Patients report a ‘plumper’ look within days, thanks to enhanced hydration and texture.”
One common question: *Is Rejuran safe for sensitive skin?* Clinical trials involving over 1,200 participants across Asia showed a **less than 2% incidence of adverse reactions**, making it suitable for most skin types. For context, laser treatments carry a higher risk of post-inflammatory hyperpigmentation, especially in Fitzpatrick skin types IV–VI. A 2023 survey by Korea’s leading aesthetic platform, Gangnam Momma, found that **89% of users** preferred Rejuran over ablative lasers due to its gentler mechanism and shorter recovery time (often **24–48 hours** vs. 7–10 days for fractional lasers).
The economic angle also matters. While a single laser session averages **$300–$800**, Rejuran treatments cost **$400–$1,200 per session**, depending on the region. However, its longer-lasting results—up to **12–18 months** with proper maintenance—mean fewer repeat visits. Take Maria, a 42-year-old marketing executive from Manila, who shared her experience on Instagram: “I’ve spent $5,000 on lasers over three years. With Rejuran, I paid $1,800 for two sessions, and my skin still looks refreshed a year later.”
What about the science behind the hype? Rejuran’s PN fragments are bioengineered to match human DNA sequences, allowing deeper penetration into the dermis. Research from Seoul National University Hospital demonstrated a **17% increase in type III collagen** (critical for skin elasticity) after just one month. Comparatively, topical collagen creams only improve surface moisture by **8–12%**, according to a 2021 meta-analysis in *Cosmetic Dermatology*.
Still, skeptics ask: *Does collagen synthesis actually slow aging?* The answer lies in long-term studies. A five-year follow-up of 500 Rejuran users in Japan showed **40% fewer fine lines** and **34% less UV-induced pigmentation** than non-users. This aligns with findings from the Global Anti-Aging Consortium, which ranks collagen-stimulating treatments as a top “preventive aging” strategy for adults over 30.
In an industry crowded with quick fixes, Rejuran’s blend of biotechnology and measurable outcomes offers a compelling case. As clinics worldwide report **92% patient satisfaction rates**, it’s clear this isn’t just another trend—it’s a shift toward sustainable skin health. Whether you’re battling acne scars or early jowls, the data suggests that rebuilding collagen isn’t just about looking younger; it’s about preserving what your skin naturally loses with time.